Compile Data Set for Download or QSAR

Found 42 hits from The Asan Foundation   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355855 (N-(3-fluoro-4-((5-(3-hydroxymethyl)phenyl)pyrrolo[...) Show SMILES OCc1cccc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI InChI=1S/C32H22F2N4O4/c33-22-6-9-24(10-7-22)37-15-2-5-26(32(37)41)31(40)36-23-8-11-28(27(34)18-23)42-29-12-14-35-38-16-13-25(30(29)38)21-4-1-3-20(17-21)19-39/h1-18,39H,19H2,(H,36,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355876 (N-(4-((5-(3-cyanomethylphenyl)pyrrolo[1,2-b]pyrida...) Show SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnn4ccc(-c5cccc(CC#N)c5)c34)c(F)c2)cc1 Show InChI InChI=1S/C32H23F2N5O3/c33-22-4-6-23(7-5-22)37-30(40)32(13-14-32)31(41)38-24-8-9-27(26(34)19-24)42-28-11-16-36-39-17-12-25(29(28)39)21-3-1-2-20(18-21)10-15-35/h1-9,11-12,16-19H,10,13-14H2,(H,37,40)(H,38,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355875 (N-(4-((5-(5-amino-2-fluoro)-5-fluorophenyl)pyrrolo...) Show SMILES Nc1ccc(F)c(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C30H22F3N5O3/c31-17-1-4-19(5-2-17)36-28(39)30(11-12-30)29(40)37-20-6-8-25(24(33)16-20)41-26-9-13-35-38-14-10-21(27(26)38)22-15-18(34)3-7-23(22)32/h1-10,13-16H,11-12,34H2,(H,36,39)(H,37,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355874 (N-(4-((5-(3-amino-4-methoxy)-5-fluorophenyl)pyrrol...) Show SMILES COc1ccc(cc1N)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C31H25F2N5O4/c1-41-26-8-2-18(16-24(26)34)22-11-15-38-28(22)27(10-14-35-38)42-25-9-7-21(17-23(25)33)37-30(40)31(12-13-31)29(39)36-20-5-3-19(32)4-6-20/h2-11,14-17H,12-13,34H2,1H3,(H,36,39)(H,37,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355873 (N-(4-((5-(3-((ethylamino)methyl)phenyl)pyrrolo[1,2...) Show SMILES CCNCc1cccc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C33H29F2N5O3/c1-2-36-20-21-4-3-5-22(18-21)26-13-17-40-30(26)29(12-16-37-40)43-28-11-10-25(19-27(28)35)39-32(42)33(14-15-33)31(41)38-24-8-6-23(34)7-9-24/h3-13,16-19,36H,2,14-15,20H2,1H3,(H,38,41)(H,39,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355872 (N-(3-fluoro-4-((5-(3-((methylamino)methyl)phenyl)p...) Show SMILES CNCc1cccc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C32H27F2N5O3/c1-35-19-20-3-2-4-21(17-20)25-12-16-39-29(25)28(11-15-36-39)42-27-10-9-24(18-26(27)34)38-31(41)32(13-14-32)30(40)37-23-7-5-22(33)6-8-23/h2-12,15-18,35H,13-14,19H2,1H3,(H,37,40)(H,38,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355871 (N-(4-((5-(3-amino-2-methyl)-5-fluorophenyl)pyrrolo...) Show SMILES Cc1c(N)cccc1-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C31H25F2N5O3/c1-18-22(3-2-4-25(18)34)23-12-16-38-28(23)27(11-15-35-38)41-26-10-9-21(17-24(26)33)37-30(40)31(13-14-31)29(39)36-20-7-5-19(32)6-8-20/h2-12,15-17H,13-14,34H2,1H3,(H,36,39)(H,37,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355870 (N-(4-((5-(3-amino-4-methyl)-5-fluorophenyl)pyrrolo...) Show SMILES Cc1ccc(cc1N)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C31H25F2N5O3/c1-18-2-3-19(16-25(18)34)23-11-15-38-28(23)27(10-14-35-38)41-26-9-8-22(17-24(26)33)37-30(40)31(12-13-31)29(39)36-21-6-4-20(32)5-7-21/h2-11,14-17H,12-13,34H2,1H3,(H,36,39)(H,37,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355868 (N-(4-((5-(5-((dimethylamino)methyl)-2-fluorophenyl...) Show SMILES CN(C)Cc1ccc(F)c(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C33H28F3N5O3/c1-40(2)19-20-3-9-26(35)25(17-20)24-12-16-41-30(24)29(11-15-37-41)44-28-10-8-23(18-27(28)36)39-32(43)33(13-14-33)31(42)38-22-6-4-21(34)5-7-22/h3-12,15-18H,13-14,19H2,1-2H3,(H,38,42)(H,39,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355867 (N-(4-((5-(2-chloro-5-((dimethylamino)methyl)phenyl...) Show SMILES CN(C)Cc1ccc(Cl)c(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C33H28ClF2N5O3/c1-40(2)19-20-3-9-26(34)25(17-20)24-12-16-41-30(24)29(11-15-37-41)44-28-10-8-23(18-27(28)36)39-32(43)33(13-14-33)31(42)38-22-6-4-21(35)5-7-22/h3-12,15-18H,13-14,19H2,1-2H3,(H,38,42)(H,39,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355866 (N-(4-((5-(3-(ethylamino)phenyl)pyrrolo[1,2-b]pyrid...) Show SMILES CCNc1cccc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C32H27F2N5O3/c1-2-35-23-5-3-4-20(18-23)25-13-17-39-29(25)28(12-16-36-39)42-27-11-10-24(19-26(27)34)38-31(41)32(14-15-32)30(40)37-22-8-6-21(33)7-9-22/h3-13,16-19,35H,2,14-15H2,1H3,(H,37,40)(H,38,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355865 (N-(4-((5-(3-aminomethylphenyl)pyrrolo[1,2-b]pyrida...) Show SMILES NCc1cccc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C31H25F2N5O3/c32-21-4-6-22(7-5-21)36-29(39)31(12-13-31)30(40)37-23-8-9-26(25(33)17-23)41-27-10-14-35-38-15-11-24(28(27)38)20-3-1-2-19(16-20)18-34/h1-11,14-17H,12-13,18,34H2,(H,36,39)(H,37,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355864 (N-(4-((5-(3-amino-5-cyanophenyl)pyrrolo[1,2-b]pyri...) Show SMILES Nc1cc(cc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12)C#N Show InChI InChI=1S/C31H22F2N6O3/c32-20-1-3-22(4-2-20)37-29(40)31(9-10-31)30(41)38-23-5-6-26(25(33)16-23)42-27-7-11-36-39-12-8-24(28(27)39)19-13-18(17-34)14-21(35)15-19/h1-8,11-16H,9-10,35H2,(H,37,40)(H,38,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355863 (N-(4-((5-(3-((dimethylamino)methyl)phenyl)pyrrolo[...) Show SMILES CN(C)Cc1cccc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C33H29F2N5O3/c1-39(2)20-21-4-3-5-22(18-21)26-13-17-40-30(26)29(12-16-36-40)43-28-11-10-25(19-27(28)35)38-32(42)33(14-15-33)31(41)37-24-8-6-23(34)7-9-24/h3-13,16-19H,14-15,20H2,1-2H3,(H,37,41)(H,38,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355862 (N-(4-((5-(3-((dimethylamino)methyl)phenyl)pyrrolo[...) Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4cccc(CN(C)C)c4)c23)c(F)c1 Show InChI InChI=1S/C36H31F2N5O4/c1-4-46-31-16-18-42(27-11-8-25(37)9-12-27)36(45)33(31)35(44)40-26-10-13-30(29(38)21-26)47-32-14-17-39-43-19-15-28(34(32)43)24-7-5-6-23(20-24)22-41(2)3/h5-21H,4,22H2,1-3H3,(H,40,44)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355861 (4-ethoxy-N-(3-fluoro-4-((5-(3-aminophenyl)pyrrolo[...) Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4cccc(N)c4)c23)c(F)c1 Show InChI InChI=1S/C33H25F2N5O4/c1-2-43-28-14-16-39(24-9-6-21(34)7-10-24)33(42)30(28)32(41)38-23-8-11-27(26(35)19-23)44-29-12-15-37-40-17-13-25(31(29)40)20-4-3-5-22(36)18-20/h3-19H,2,36H2,1H3,(H,38,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355860 (4-ethoxy-N-(3-fluoro-4-((5-(3-morpholin-4-carbonyl...) Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4cccc(c4)C(=O)N4CCOCC4)c23)c(F)c1 Show InChI InChI=1S/C38H31F2N5O6/c1-2-50-32-14-16-44(28-9-6-26(39)7-10-28)38(48)34(32)36(46)42-27-8-11-31(30(40)23-27)51-33-12-15-41-45-17-13-29(35(33)45)24-4-3-5-25(22-24)37(47)43-18-20-49-21-19-43/h3-17,22-23H,2,18-21H2,1H3,(H,42,46)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355859 (4-ethoxy-N-(3-fluoro-4-((5-(pyrimidin-5-yl)pyrrolo...) Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4cccc(CN5CCOCC5)c4)c23)c(F)c1 Show InChI InChI=1S/C38H33F2N5O5/c1-2-49-33-14-16-44(29-9-6-27(39)7-10-29)38(47)35(33)37(46)42-28-8-11-32(31(40)23-28)50-34-12-15-41-45-17-13-30(36(34)45)26-5-3-4-25(22-26)24-43-18-20-48-21-19-43/h3-17,22-23H,2,18-21,24H2,1H3,(H,42,46)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355853 (4-ethoxy-N-(3-fluoro-4-((5-pyridin-4-yl)pyrrolo[1,...) Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4ccncc4)c23)c(F)c1 Show InChI InChI=1S/C32H23F2N5O4/c1-2-42-27-13-17-38(23-6-3-21(33)4-7-23)32(41)29(27)31(40)37-22-5-8-26(25(34)19-22)43-28-11-16-36-39-18-12-24(30(28)39)20-9-14-35-15-10-20/h3-19H,2H2,1H3,(H,37,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355854 (4-ethoxy-N-(3-fluoro-4-((5-(3-formylphenyl)pyrrolo...) Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4cccc(C=O)c4)c23)c(F)c1 Show InChI InChI=1S/C34H24F2N4O5/c1-2-44-29-14-16-39(25-9-6-23(35)7-10-25)34(43)31(29)33(42)38-24-8-11-28(27(36)19-24)45-30-12-15-37-40-17-13-26(32(30)40)22-5-3-4-21(18-22)20-41/h3-20H,2H2,1H3,(H,38,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355869 (N-(4-((5-(3-((dimethylamino)methyl)-5-fluorophenyl...) Show SMILES CN(C)Cc1cc(F)cc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C33H28F3N5O3/c1-40(2)19-20-15-21(17-23(35)16-20)26-10-14-41-30(26)29(9-13-37-41)44-28-8-7-25(18-27(28)36)39-32(43)33(11-12-33)31(42)38-24-5-3-22(34)4-6-24/h3-10,13-18H,11-12,19H2,1-2H3,(H,38,42)(H,39,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355856 (4-ethoxy-N-(3-fluoro-4-((5-(3-(2-hydroxypropan-2-y...) Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4cccc(c4)C(C)(C)O)c23)c(F)c1 Show InChI InChI=1S/C36H30F2N4O5/c1-4-46-30-16-18-41(26-11-8-24(37)9-12-26)35(44)32(30)34(43)40-25-10-13-29(28(38)21-25)47-31-14-17-39-42-19-15-27(33(31)42)22-6-5-7-23(20-22)36(2,3)45/h5-21,45H,4H2,1-3H3,(H,40,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355857 (4-ethoxy-N-(3-fluoro-4-((5-(3-(1-hydroxyethyl)phen...) Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4cccc(c4)C(C)O)c23)c(F)c1 Show InChI InChI=1S/C35H28F2N4O5/c1-3-45-30-15-17-40(26-10-7-24(36)8-11-26)35(44)32(30)34(43)39-25-9-12-29(28(37)20-25)46-31-13-16-38-41-18-14-27(33(31)41)23-6-4-5-22(19-23)21(2)42/h4-21,42H,3H2,1-2H3,(H,39,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM355858 (N-(3-fluoro-4-((5-(3-(1-hydroxyethyl)phenyl)pyrrol...) Show SMILES CC(O)c1cccc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI InChI=1S/C33H24F2N4O4/c1-20(40)21-4-2-5-22(18-21)26-14-17-39-31(26)30(13-15-36-39)43-29-12-9-24(19-28(29)35)37-32(41)27-6-3-16-38(33(27)42)25-10-7-23(34)8-11-25/h2-20,40H,1H3,(H,37,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...				US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM117067 (US8664230, 3) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(OC3CCOCC3)c2n1 Show InChI InChI=1S/C23H18ClF2N5O4S/c24-22-19(31-36(32,33)20-4-1-14(25)10-16(20)26)9-13(11-27-22)17-2-3-18-21(30-17)23(29-12-28-18)35-15-5-7-34-8-6-15/h1-4,9-12,15,31H,5-8H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM117067 (US8664230, 3) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(OC3CCOCC3)c2n1 Show InChI InChI=1S/C23H18ClF2N5O4S/c24-22-19(31-36(32,33)20-4-1-14(25)10-16(20)26)9-13(11-27-22)17-2-3-18-21(30-17)23(29-12-28-18)35-15-5-7-34-8-6-15/h1-4,9-12,15,31H,5-8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM117068 (US8664230, 4) Show SMILES CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C24H21ClF2N6O3S/c1-33-8-6-16(7-9-33)36-24-22-19(29-13-30-24)4-3-18(31-22)14-10-20(23(25)28-12-14)32-37(34,35)21-5-2-15(26)11-17(21)27/h2-5,10-13,16,32H,6-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM117067 (US8664230, 3) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(OC3CCOCC3)c2n1 Show InChI InChI=1S/C23H18ClF2N5O4S/c24-22-19(31-36(32,33)20-4-1-14(25)10-16(20)26)9-13(11-27-22)17-2-3-18-21(30-17)23(29-12-28-18)35-15-5-7-34-8-6-15/h1-4,9-12,15,31H,5-8H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM117068 (US8664230, 4) Show SMILES CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C24H21ClF2N6O3S/c1-33-8-6-16(7-9-33)36-24-22-19(29-13-30-24)4-3-18(31-22)14-10-20(23(25)28-12-14)32-37(34,35)21-5-2-15(26)11-17(21)27/h2-5,10-13,16,32H,6-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM117065 (US8664230, 1) Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2ncnc(Oc3cccnc3)c2n1)c1ccccc1 Show InChI InChI=1S/C23H16N6O3S/c30-33(31,19-6-2-1-3-7-19)29-17-11-16(12-25-13-17)20-8-9-21-22(28-20)23(27-15-26-21)32-18-5-4-10-24-14-18/h1-15,29H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM117066 (US8664230, 2) Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2ncnc(OC3CCOCC3)c2n1)c1ccccc1 Show InChI InChI=1S/C23H21N5O4S/c29-33(30,19-4-2-1-3-5-19)28-17-12-16(13-24-14-17)20-6-7-21-22(27-20)23(26-15-25-21)32-18-8-10-31-11-9-18/h1-7,12-15,18,28H,8-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM117070 (US8664230, 6) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(NC3CCOCC3)c2n1 Show InChI InChI=1S/C23H19ClF2N6O3S/c24-22-19(32-36(33,34)20-4-1-14(25)10-16(20)26)9-13(11-27-22)17-2-3-18-21(31-17)23(29-12-28-18)30-15-5-7-35-8-6-15/h1-4,9-12,15,32H,5-8H2,(H,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM117069 (US8664230, 5) Show SMILES CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cncc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C24H24N6O3S/c1-30-11-9-19(10-12-30)33-24-23-22(26-16-27-24)8-7-21(28-23)17-13-18(15-25-14-17)29-34(31,32)20-5-3-2-4-6-20/h2-8,13-16,19,29H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM117066 (US8664230, 2) Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2ncnc(OC3CCOCC3)c2n1)c1ccccc1 Show InChI InChI=1S/C23H21N5O4S/c29-33(30,19-4-2-1-3-5-19)28-17-12-16(13-24-14-17)20-6-7-21-22(27-20)23(26-15-25-21)32-18-8-10-31-11-9-18/h1-7,12-15,18,28H,8-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM117069 (US8664230, 5) Show SMILES CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cncc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C24H24N6O3S/c1-30-11-9-19(10-12-30)33-24-23-22(26-16-27-24)8-7-21(28-23)17-13-18(15-25-14-17)29-34(31,32)20-5-3-2-4-6-20/h2-8,13-16,19,29H,9-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM117070 (US8664230, 6) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(NC3CCOCC3)c2n1 Show InChI InChI=1S/C23H19ClF2N6O3S/c24-22-19(32-36(33,34)20-4-1-14(25)10-16(20)26)9-13(11-27-22)17-2-3-18-21(31-17)23(29-12-28-18)30-15-5-7-35-8-6-15/h1-4,9-12,15,32H,5-8H2,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM117065 (US8664230, 1) Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2ncnc(Oc3cccnc3)c2n1)c1ccccc1 Show InChI InChI=1S/C23H16N6O3S/c30-33(31,19-6-2-1-3-7-19)29-17-11-16(12-25-13-17)20-8-9-21-22(28-20)23(27-15-26-21)32-18-5-4-10-24-14-18/h1-15,29H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM117066 (US8664230, 2) Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2ncnc(OC3CCOCC3)c2n1)c1ccccc1 Show InChI InChI=1S/C23H21N5O4S/c29-33(30,19-4-2-1-3-5-19)28-17-12-16(13-24-14-17)20-6-7-21-22(27-20)23(26-15-25-21)32-18-8-10-31-11-9-18/h1-7,12-15,18,28H,8-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM117069 (US8664230, 5) Show SMILES CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cncc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C24H24N6O3S/c1-30-11-9-19(10-12-30)33-24-23-22(26-16-27-24)8-7-21(28-23)17-13-18(15-25-14-17)29-34(31,32)20-5-3-2-4-6-20/h2-8,13-16,19,29H,9-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM117065 (US8664230, 1) Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2ncnc(Oc3cccnc3)c2n1)c1ccccc1 Show InChI InChI=1S/C23H16N6O3S/c30-33(31,19-6-2-1-3-7-19)29-17-11-16(12-25-13-17)20-8-9-21-22(28-20)23(27-15-26-21)32-18-5-4-10-24-14-18/h1-15,29H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM117068 (US8664230, 4) Show SMILES CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C24H21ClF2N6O3S/c1-33-8-6-16(7-9-33)36-24-22-19(29-13-30-24)4-3-18(31-22)14-10-20(23(25)28-12-14)32-37(34,35)21-5-2-15(26)11-17(21)27/h2-5,10-13,16,32H,6-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM117070 (US8664230, 6) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(NC3CCOCC3)c2n1 Show InChI InChI=1S/C23H19ClF2N6O3S/c24-22-19(32-36(33,34)20-4-1-14(25)10-16(20)26)9-13(11-27-22)17-2-3-18-21(31-17)23(29-12-28-18)30-15-5-7-35-8-6-15/h1-4,9-12,15,32H,5-8H2,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair